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Listing of IPOX Stains > Stain Description

Stain Name Antibody Description
MMR Markers (MLH-1, MSH2, MSH6, PMS2 MMR Markers (MLH-1, MSH2, MSH6, PMS2) Used in the identification of MSI colorectal tumors as mismatch repair deficiency may serve as a prognostic marker of patient outcome, a predictive marker of response to chemotherapy, and as a screening tool for hereditary nonpolyposis colon cancer, (HNPCC)(Lynch Syndrome). HNPCC related tumors also include endometrial, stomach, ovarian, pancreas, bladder, ureter and renal pelvis, biliary tract, brain (usually glioblastoma as seen in Turcot Syndrome), sebaceous gland adenomas and keratoacanthomas in Muir-Torre Syndrome, carcinoma of the small bowel.